Alexis Mikes Kalergis Parra

Proyectos adjudicados

• CLINICAL EVALUATION OF A HUMAN MONOCLONAL N-SPECIFIC ANTIBODY AS A NEW THERAPY FOR RSV. (2019) Fuente: Copec UC(Santiago;CL) | Rol:
• BIOMEDICAL RESEARCH CONSORTIUM (2013) Fuente: Corporación de Fomento de la Producción(Santiago;Please select...;CL) | Rol:
• CHARACTERIZATION OF THE CLINICAL AND IMMUNOLOGICAL RESPONSES TRIGGERED BY A BCG-BASED RECOMBINANT VACCINE IN HEALTHY VOLUNTEERS (2019) Fuente: FONDECYT(Santiago;CL) | Rol:
• CHARACTERIZATION OF A RECOMBINANT VACCINE AGAINST THE RESPIRATORY SYNCYTIAL VIRUS (2016) Fuente: FONDEF(Santiago;CL) | Rol:
• NOUVELLES EQUIPES-NOUVELLES THÉMATIQUES (2012) Fuente: La Région Pays De La Loire(Nantes;FR) | Rol:
• ANALYSIS OF DENDRITIC CELL FUNCTION IN SYSTEMIC LUPUS ERYTHEMATOSUS: IMPLICATIONS ON IMMUNOTHERAPY (2007) Fuente: PBCT Network (Santiago;CL) | Rol:
• DESIGN OF A MANUFACTURE PROGRAM FOR VACCINES AND ANTIBODIES FOR DIAGNOSIS AND THERAPIES IN THE METROPOLITAN REGION (2014) Fuente: CONICYT Grant VCE (Santiago;CL) | Rol:
• VALORIZATION OF INVESTIGATION RESULTS (2010) Fuente: Fondo de Fomento al Desarrollo Científico y Tecnológico(Santiago;CL) | Rol:
• INDUCING CELLULAR IMMUNITY AGAINST PISCIRICKETTSIA SALMONIS IN SALMON BY IMMUNE COMPLEX VACCINATION (2004) Fuente: International Foundation for Science(Stockholm;SE) | Rol:
• CHARACTERIZATION OF A RECOMBINANT VACCINE AGAINST SYNCYTIAL RESPIRATORY VIRUS. PÁGINA (2013) Fuente: FONDEF(Santiago;Please select...;CL) | Rol:
• DEVELOPMENT OF NEW DIAGNOSTIC TOOLS FOR DETECTION OF RESPIRATORY VIRUSES (2007) Fuente: FONDEF(Santiago;Please select...;CL) | Rol:
• ROLE OF IL-10 IN THE ABILITY OF BACTERIAL PATHOGENS TO CAUSE SYSTEMIC INFECTIONS IN THE HOST (2014) Fuente: Fondo Nacional de Desarrollo Científico y Tecnológico(Santiago;Please select...;CL) | Rol:
• EVALUATION OF SALMONELLA ENTERICA CAPACITY TO PROMOTE INFLAMMATORY BOWEL DISEASE IN SUSCEPTIBLE HOSTS (2010) Fuente: Fondo Nacional de Desarrollo Científico y Tecnológico(Santiago;Please select...;CL) | Rol:
• MILLENIUM NUCLEUS ON IMMUNOLOGY AND IMMUNOTHERAPY (2005) Fuente: Ministry of Economy(Santiago;Please select...;CL) | Rol:
• DETECTION KIT FOR RESPIRATORY VIRUSES INCORPORATING A PREDICTOR OF PATIENT``S IMMUNE RESPONSE TO ESTABLISH SEVERITY OF INFECTION (2012) Fuente: Corporación de Fomento de la Producción(Santiago;Please select...;CL) | Rol:
• MOLECULAR MECHANISMS DEVELOPED BY PATHOGENIC BACTERIA TO EVADE ADAPTIVE IMMUNITY. (2007) Fuente: Fondo Nacional de Desarrollo Científico y Tecnológico(Santiago;Please select...;CL) | Rol:
• T CELL RESPONSES AND DENDRITIC CELL FUNCTION DURING SYSTEMIC LUPUS ERYTHEMATOSUS (2011) Fuente: Fondo Nacional de Desarrollo Científico y Tecnológico(Santiago;Please select...;CL) | Rol:
• DENDRITIC CELL FUNCTION IN SYSTEMIC LUPUS ERYTHEMATOSUS (2005) Fuente: Fondo Nacional de Desarrollo Científico y Tecnológico(Santiago;Please select...;CL) | Rol:
• VALIDATION OF A DIAGNOSIS METHOD OF VIRAL RESPIRATORY INFECTION IN NASOPHARYNGEAL SECRETIONS (2015) Fuente: Corporación de Fomento de la Producción(Santiago;CL) | Rol:
• DESARROLLO DE UNA VACUNA BIVALENTE CONTRA LA INFECCIÓN RESPIRATORIA CAUSADA POR EL VIRUS RESPIRATORIO SINCICIAL Y POR METAPNEUMOVIRUS HUMANO (2018) Fuente: INNOVA-CORFO (17ITE1-89261) | Rol: COINVESTIGADOR(A)
• DEVELOPMENT OF A NEW ANTI-VIRAL ANTIBODY AGAINST THE RESPIRATORY SYNCYTIAL VIRUS (2018) Fuente: Fundación Copec-UC (2016.R.772) | Rol: DIRECTOR(A)
• INTERNATIONAL APPROVAL OF VACCINE FORMULATIONS DEVELOPED IN CHILE=> SUBMISSION OF THE RBCG-N-HRSV TO FOOD AND DRUG ADMINISTRATION FDA AGENCY (2016) Fuente: 19. IV Concurso Programa Acelerador UC (-) | Rol: INV. PRINCIPAL
• CHARACTERIZATION AND FUNCTIONAL RELEVANCE OF THE T CELL RECEPTOR REPERTOIRE OF HRSV-SPECIFIC T CELLS EXPANDED IN RESPONSE TO HRSV INFECTION IN NAIVE AND VACCINATED MICE. (2015) Fuente: FONDECYT (3160249) | Rol: INV. PATROCINANTE
• ELUCIDATING THE MECHANISMS OF PATHOGENICITY USED BY THE HUMAN RESPIRATORY SYNCYTIAL VIRUS TO PREVENT T CELL ACTIVATION AND CAUSE CENTRAL NERVOUS SYSTEM INFLAMMATION. (2015) Fuente: FONDECYT (1150862) | Rol: INV. RESPONSABLE
• HO-1 EXPRESSION PROTECTS FROM KIDNEY DAMAGE INDUCED BY INNATE IMMUNITY DURING LUPUS NEPHRITIS (2015) Fuente: FONDECYT (1150173) | Rol: COINVESTIGADOR(A)
• ROLE OF HERPES SIMPLEX VIRUS 2 HSV-2 SURFACE GLYCOPROTEINS OVER DENDRITIC CELL FUNCTION (2014) Fuente: FONDECYT (1140011) | Rol: COINVESTIGADOR(A)
• ROLE OF INTERLEUKIN 10 IL-10 IN THE ABILITY OF BACTERIAL PATHOGENS TO CAUSE SYSTEMIC INFECTIONS IN THE HOST. (2014) Fuente: FONDECYT (1140010) | Rol: COINVESTIGADOR(A)
• ROLE OF THYROID HORMONES ON IMMUNE SYSTEM FUNCTION=> EVALUATION OF CD8+ T CELLS IN RSV INFECTION UNDER MATERNAL HYPHOTIROXINEMIA. (2014) Fuente: FONDECYT (3150559) | Rol: INV. PATROCINANTE
• STUDY OF THE MATERNAL HYPOTHYROXINEMIA EFFECT ON THE OFFSPRING T CELL RESPONSE AGAINST CENTRAL NERVOUS SYSTEM ANTIGENS DURING EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS (2013) Fuente: FONDECYT (1130996) | Rol: COINVESTIGADOR(A)
• ASSESSMENT OF RATIONALLY DESIGNED SMALL MOLECULE INHIBITORS TARGETING THE HUMAN RESPIRATORY SYNCYTIAL VIRUS MATRIX PROTEIN (2013) Fuente: FONDECYT (1131065) | Rol: COINVESTIGADOR(A)
• DESARROLLO DE INMUNOTERAPIA CELULAR PARA EL TRATAMIENTO DEL LUPUS ERITEMATOSO SISTÉMICO BASADA EN CÉLULAS DENDRÍTICAS AUTÓLOGAS (2013) Fuente: CORFO INNOVA (12IDL2-15146) | Rol: COINVESTIGADOR(A)
• ROLE OF HEME OXYGENASE-1 IN ACUTE AND CHRONIC INTESTINAL INFLAMATION=> INFECTIOUS AND IMMUNE MODELS. (2013) Fuente: FONDECYT (1131012) | Rol: COINVESTIGADOR(A)
• SALT INTAKE IN ESSENTIAL HYPERTENSION=> STUDIES OF NEW BIOCHEMICAL AND GENETIC MECHANISMS TO IDENTIFY ITS ETIOLOGY (2013) Fuente: FONDECYT (1130427) | Rol: COINVESTIGADOR(A)
• ESTUDIO DE LA RESPUESTA INMUNE MODULADAS POR CELULAS EPITELIALES HUMANAS HACIA EL VIRUS RESPIRATORIO SINCICIAL Y EL METAPNEUMOVIRUS HUMANO (2011) Fuente: FONDECYT (3120019) | Rol: INV. PATROCINANTE
• IDENTIFICATION OF THE MECHANISMS USED BY THE RESPIRATORY SYNCYTIAL VIRUS RSV TO INTERFERE WITH THE FUNCTION OF DENDRITIC CELLS AND IMPAIR T CELL IMMUNITY IN THE HOST (2011) Fuente: FONDECYT (1110397) | Rol: DIRECTOR(A)
• MILLENNIUM INSTITUTE ON IMMUNOLOGY AND IMMUNOTHERAPY (2011) Fuente: Programa ICM- Ministerio de Economía (P09-016-F) | Rol: INV. PRINCIPAL
• ROLE OF DENDRITIC CELLS AT DRIVING THE T CELL RESPONSE LEADING TO SYSTEMIC LUPUS ERYTHEMATOSUS=> IMPLICATIONS AS A NOVEL MECHANISM FOR THERAPEUTIC TARGETING (2011) Fuente: FONDECYT (1110518) | Rol: COINVESTIGADOR(A)
• MATERNAL HYPOTHYROXINEMIA INCREASES THE SUSCEPTIBILITY TO DEVELOP INFLAMMATORY DEMYELINATION IN THE OFFSPRING (2010) Fuente: FONDECYT (1100926) | Rol: COINVESTIGADOR(A)
• MODULATION OF T CELL ACTIVATION BY HUMAN METAPNEUMOVIRUS-INFECTED DENDRITIC CELLS (2009) Fuente: FONDECYT (3100090) | Rol: INV. PATROCINANTE
• ESTUDIO DE LA EXPRESION Y REGULACION DIFERENCIAL DE LOS RECEPTORES FCY ACTIVADORES E INHIBIDORES EN LA CELULA DENDRITICA EN LUPUS ERIMATOSO SISTEMICO=> IMPACTO EN LA ACTIVACION DE LINFOCITOS Y AUTORREACTIVOS (2008) Fuente: FONDECYT (1085281) | Rol: COINVESTIGADOR(A)
• CARACTERIZACION CELULAR Y MOLECULAR DE UN NUEVO MECANISMO DE PATOGENICIDAD DE SALMONELLA=> INHIBICION DE LA CAPACIDAD DE LA CELULA DENDRITICA DE ACTIVAR A LINFOCITOS T PARA EVADIR LA RESPUESTA INMUNE ADQUIRIDA DEL HOSPEDERO (2007) Fuente: FONDECYT (1070352) | Rol: DIRECTOR(A)
• CONSORCIO TECNOLÓGICO EN BIOMEDICINA APLICADA PARA EL DESARROLLO DE NUEVAS ESTRATEGIAS DE PREVENCIÓN DIAGNÓSTICO Y TRATAMIENTO DE ENFERMEDADES HUMANAS (2007) Fuente: CORFO INNOVA (-) | Rol: INV. PRINCIPAL
• DEVELOPMENT OF A NEW DRUG AGAINST TUMORS IN CANCERS OF THE FEMALE THE REPRODUCTIVE TRACT (2007) Fuente: FONDEF (D06I1017) | Rol: COINVESTIGADOR(A)
• DEVELOPMENT OF RAPID IMMUNOCHROMATOGRAPHIC KITS FOR THE DETECTION OF RESPIRATORY VIRUSES RELEVANT FOR PUBLIC HEALTH (2007) Fuente: FONDEF (D06I1008) | Rol: INV. PRINCIPAL
• PAPEL DE LA VIDA MEDIA DE INTERACCION TCR/PMHC EN LA ACTIVACION DE CELULAS T DE MEMORIA. (2007) Fuente: FONDECYT (3070018) | Rol: INV. PATROCINANTE
• ROLE OF HEME-OXIGENASE-1 AND CARBON MONOXIDE IN ANTIGEN PRESENTATION BY DENDRITIC CELLS (2007) Fuente: ECOS-CONICYT (-) | Rol: INV. PRINCIPAL
• MILLENNIUM NUCLEUS IN IMMUNOLOGY AND IMMUNOTHERAPY P04/030F (2006) Fuente: MIDEPLAN (.P04/030F) | Rol: INV. PRINCIPAL
• BACTERIAL RECOMBINANT VACCINE AGAINST SYNCYTIAL RESPIRATORY VIRUS (2005) Fuente: Grant UC | Rol: INV. PRINCIPAL
• EVALUACION DEL ESTADO FUNCIONAL DE LAS CELULAS DENDRITICAS EN EL LUPUS ERITEMATOSO SISTEMICO (2005) Fuente: FONDECYT (1050979) | Rol: COINVESTIGADOR(A)
• GENERACIÓN DE UNA VACUNA RECOMBINANTE CONTRA EL VIRUS RESPIRATORIO SINCICIAL (2005) Fuente: FONDEF (D04I1075) | Rol: DIRECTOR(A)
• IDENTIFICACION DE LOS MECANISMOS MOLECULARES UTILIZADOS POR SALMONELLA ENTERICA SEROVAR TYPHIMURIUM PARA INTERFERIR CON LA FUNCION DE LA CELULA DENDRITICA Y EVADIR LA RESPUESTA INMUNE ADQUIRIDA. (2005) Fuente: FONDECYT (3060041) | Rol: INV. PATROCINANTE
• ANTI BACTERIAL T CELL IMMUNITY (2004) Fuente: IFS | Rol: INV. PRINCIPAL
• ESTUDIO DE LAS INTERACCIONES MOLECULARES NECESARIAS PARA LA SINAPSIS INMUNOLOGICA ENTRE LA CELULA DENDRITICA Y EL LINFOCITO T=> IMPLICACIONES EN LA INMUNIDAD ANTI-BACTERIANA (2003) Fuente: FONDECYT (7030038) | Rol: INV. PRINCIPAL
• ROLE OF DENDRITIC CELLS AND T CELLS IN PROTECTIVE IMMUNITY AGAINST BACTERIA (2002) Fuente: DIPUC | Rol: INV. PRINCIPAL
• PARTICIPACION DE ANTIGENOS MITOCONDRIALES EN LA DERMATITIS DE CONTACTO CAUSADA POR EL ALERGENO DEL LITRE=> LITREOL 3-PENTADECIL10-ENCATECOL (2000) Fuente: FONDECYT (1000203) | Rol: COINVESTIGADOR(A)
• CARACTERIZACIÓN DE UNA VACUNA RECOMBINANTE CONTRA EL VIRUS RESPIRATORIO SINCICIAL (2016) Fuente: FONDEF (D11E1080) | Rol: DIRECTOR(A)

Tus publicaciones

• MUCOSAL VACCINATION WITH LACTOCOCCUS LACTIS-SECRETING SURFACE IMMUNOLOGICAL PROTEIN INDUCES HUMORAL AND CELLULAR IMMUNE PROTECTION AGAINST GROUP B STREPTOCOCCUS IN A MURINE MODEL Autores: Diaz-Dinamarca; Diego A.; Hernandez; Carlos; Escobar; Daniel F.; Soto; Daniel A.; Muñoz; Guillermo A.; Badilla; Jesús F.; Manzo; Ricardo A.; Carrión; Flavio; Kalergis; Alexis M; Vasquez; Abel E. Año: 2020
• SURFACE IMMUNOGENIC PROTEIN OF STREPTOCOCCUS GROUP B IS AN AGONIST OF TOLL-LIKE RECEPTORS 2 AND 4 AND A POTENTIAL IMMUNE ADJUVANT Autores: Diaz-Dinamarca; Diego A.; Manzo; Ricardo A.; Soto; Daniel A.; Avendaño-Valenzuela; María José; Bastias; Diego N.; Soto; Paulina I.; Escobar; Daniel F.; Vasquez-Saez; Valeria; Carrión; Flavio; Pizarro-Ortega; Magdalena S.; Wilson; Christian A. M.; Berrios; Julio; Kalergis; Alexis M; Vasquez; Abel E. Año: 2020
• MODULATION OF IMMUNE CELLS AS A THERAPY FOR CUTANEOUS LUPUS ERYTHEMATOSUS Autores: Jorge Soto ;Felipe Melo-Gonzalez;Claudia A. Riedel;Susan M. Bueno;Alexis Kalergis ; Año: 2022 Link: https://doi.org/10.3390/ijms231810706
• INCREASED HEME OXYGENASE 1 EXPRESSION UPON A PRIMARY EXPOSURE TO THE RESPIRATORY SYNCYTIAL VIRUS AND A SECONDARY MYCOBACTERIUM BOVIS INFECTION Autores: Gisela Canedo-Marroquin;Jorge A. Soto;Catalina A. Andrade;Susan M. Bueno;Alexis Kalergis ; Año: 2022 Link: https://doi.org/10.3390/antiox11081453
• INTERPLAY BETWEEN LIPID METABOLISM LIPID DROPLETS AND DNA VIRUS INFECTIONS Autores: Mónica Farías León;Benjamin Diethelm-Varela;Areli J. Navarro;Alexis Kalergis ;Gonzalez, PA; Año: 2022 Link: https://doi.org/10.3390/cells11142224
• SAFETY AND NON-INFERIORITY EVALUATION OF TWO IMMUNIZATION SCHEDULES WITH AN INACTIVATED SARS-COV-2 VACCINE IN ADULTS: A RANDOMIZED CLINICAL TRIAL Autores: KATIA ABARCA;Carolina Iturriaga;Marcela Urzúa;Nicole Le Corre;Augusto Pineda;Carolina Fernández;Angélica Domínguez;Gonzalez, PA;Susan M. Bueno;Paulina Donato;Pilar Espinoza;Daniela Fuentes;Marcela González;Paula Guzmán;Paula Muñoz-Venturelli;Carlos M. Pérez;Marcela Potin;Álvaro Rojas;González-Aramundiz JV;Nicolás Marcelo Salvador Gálvez Arriagada;Francisca Aguirre-Boza;Sofía Aljaro Ehrenberg;Luis Federico Batiz;Yessica Campisto;Mariela Cepeda;Aarón Cortés;Sofia Lopez Coloma;María Loreto Pérez;Andrea Schilling;Alexis Kalergis ;on behalf of the CoronaVac03CL Study Group; Año: 2022 Link: https://doi.org/10.3390/vaccines10071082
• RISK FACTORS FROM PREGNANCY TO ADULTHOOD IN MULTIPLE SCLEROSIS OUTCOME Autores: Enrique M. González-Madrid;Ma. Andreina Rangel-Ramírez;María José Mendoza-León;Oscar Álvarez-Mardones;Gonzalez, PA;Alexis Kalergis ;Maria Cecilia Opazo;Ma Andreina Rangel-Ramírez; Año: 2022 Link: https://doi.org/10.3390/ijms23137080
• BCG-BASED VACCINES ELICIT ANTIGEN-SPECIFIC ADAPTIVE AND TRAINED IMMUNITY AGAINST SARS-COV-2 AND ANDES ORTHOHANTAVIRUS Autores: Jorge A. Soto;Fabián E. Díaz;Angello Retamal-Díaz;Nicolás Marcelo Salvador Gálvez Arriagada;Felipe Melo-González;Alejandro Piña-Iturbe;Mario A. Ramírez;Karen Bohmwald;Gonzalez, PA;Susan M. Bueno;Alexis Kalergis ; Año: 2022 Link: https://doi.org/10.3390/vaccines10050721
• LIMITED HEME OXYGENASE CONTRIBUTION TO MODULATING THE SEVERITY OF SALMONELLA ENTERICA SEROVAR TYPHIMURIUM INFECTION Autores: Valentina Sebastian;Daniela Moreno Tapia;Felipe Melo-Gonzalez;María P. Hernández-Cáceres;Geraldyne A. Salazar;Catalina Pardo-Roa;Mónica Farías León;Omar P. Vallejos;Bárbara M. Schultz;Eugenia Morselli;Manuel M. Álvarez-Lobos;Gonzalez, PA;Alexis Kalergis ;Susan M. Bueno; Año: 2022 Link: https://doi.org/10.3390/antiox11061040
• NEUROTROPHIN SIGNALING IMPAIRMENT BY VIRAL INFECTIONS IN THE CENTRAL NERVOUS SYSTEM Autores: Karen Bohmwald;Catalina A. Andrade;Valentina P. Mora;José T. Muñoz;Robinson Ramírez;María F. Rojas;Alexis Kalergis ; Año: 2022 Link: https://doi.org/10.3390/ijms23105817
• POTENTIAL NEUROCOGNITIVE SYMPTOMS DUE TO RESPIRATORY SYNCYTIAL VIRUS INFECTION Autores: Catalina A. Andrade;Alexis Kalergis ;Karen Bohmwald; Año: 2021 Link: https://doi.org/10.3390/pathogens11010047
• THE IMPORTANCE OF NANOCARRIER DESIGN AND COMPOSITION FOR AN EFFICIENT NANOPARTICLE-MEDIATED TRANSDERMAL VACCINATION Autores: Valdivia-Olivares R.Y;Maria Rodriguez-Fernandez;María Javiera Álvarez-Figueroa;Alexis Kalergis ;González-Aramundiz JV; Año: 2021 Link: https://doi.org/10.3390/vaccines9121420
• CONTRIBUTION OF DYSREGULATED DNA METHYLATION TO AUTOIMMUNITY Autores: Samanta C. Funes;Ayleen Fernández-Fierro;Diego Rebolledo-Zelada;Juan Pablo Mackern-Oberti;Alexis Kalergis ; Año: 2021 Link: https://doi.org/10.3390/ijms222111892
• IMPACT OF HYPOXIA OVER HUMAN VIRAL INFECTIONS AND KEY CELLULAR PROCESSES Autores: Antonia Reyes;Luisa F. Duarte;Mónica A. Farías;Eduardo Tognarelli;Alexis Kalergis ;Susan M. Bueno;Gonzalez, PA; Año: 2021 Link: https://doi.org/10.3390/ijms22157954
• BACTERIAL AND VIRAL COINFECTIONS WITH THE HUMAN RESPIRATORY SYNCYTIAL VIRUS Autores: Gaspar Pacheco;Nicolás Marcelo Salvador Gálvez Arriagada;Jorge A. Soto;Catalina A. Andrade;Alexis Kalergis ; Año: 2021 Link: https://doi.org/10.3390/microorganisms9061293
• CONTRIBUTION OF PRO-INFLAMMATORY MOLECULES INDUCED BY RESPIRATORY VIRUS INFECTIONS TO NEUROLOGICAL DISORDERS Autores: Karen Bohmwald;Catalina A. Andrade;Alexis Kalergis ; Año: 2021 Link: https://doi.org/10.3390/ph14040340
• HOST COMPONENTS THAT MODULATE THE DISEASE CAUSED BY HMPV Autores: Nicolás Marcelo Salvador Gálvez Arriagada;Catalina A. Andrade;Gaspar Pacheco;Jorge A. Soto;Vicente Stranger;Thomas Rivera;AE Vasquez;Alexis Kalergis ; Año: 2021 Link: https://doi.org/10.3390/v13030519
• LAG-3 CONTRIBUTION TO T CELL DOWNMODULATION DURING ACUTE RESPIRATORY VIRAL INFECTIONS Autores: Linmar Rodríguez-Guilarte;Mario Andres Ramirez Pozo;Catalina Andrade Parra;Alexis Kalergis ; Año: 2023 Link: https://doi.org/10.3390/v15010147